What Does “Roman Canon” Mean in the Bible?

The oldest Eucharistic Prayer of the Mass in Rome. It is the first one in the Missal.

It can mean

Another name: it is also called “Eucharistic Prayer I.”
In the Bible: it recalls the offering of Melchizedek, king and priest, who brought bread and wine.

Genesis 14:18; Luke 22:19

Genesis 14:18

But Melchisedech the king of Salem, bringing forth bread and wine, for he was the priest of the most high God,

Luke 22:19

And taking bread, he gave thanks, and brake; and gave to them, saying: This is my body, which is given for you. Do this for a commemoration of me.

Douay-Rheims Bible (Challoner revision), public domain.

Source: GIRM 365; Catechism 1333 and 1353