Holy Orders
It makes a man a deacon, a priest, or a bishop, to serve the Church in the name of Christ.
The sign
The bishop lays his hands on him and says a prayer of consecration.
Who gives it
The bishop.
How many times
Each degree (deacon, priest, bishop) is received only once, and for ever.
What the Bible says
Luke 22:19
And taking bread, he gave thanks, and brake; and gave to them, saying: This is my body, which is given for you. Do this for a commemoration of me.
Douay-Rheims Bible (Challoner revision), public domain.
Source: Catechism 611, 1337, 1536, 1554, 1573, 1576, and 1582